Tennessee State University
Department of Chemistry


 

  
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Publications 

1.    Jongoh Choi, Tiffany L. Wilson, Ana M. Ly, Cosmas O. Okoro, Udobi C. Onubogu, and   Kinfe K. Redda, “Synthesis of Some N-(phenylsulfonylamino)-1,2,3,6-Tetrahydropyridines as Potential Anti-inflammatory Agents.” Med. Chem. Res. 1995, 5, 281-295.

2.   Clanicia A. Pelle, Cosmas O. Okoro, Tiffany L. Wilson, Udobi C. Onubogu, Kyoung-Jin   Yoon, and Kinfe K. Redda, ‘Synthesis of Several N-(Substituted Phenylcarbonylamino)-4-(3-Cyclohexenyl)-1,2,3,6-Tetrahydropyridines as potential Anti-inflammatory Agents.” Synth. Commun. 1996, 26(14), 2703-2714.

3.   Cosmas O. Okoro, Tiffany L. Wilson, Jongoh Choi, and Kinfe K. Redda, “Synthesis and       Antiinflammatory Activity Determination of Some N-(Substituted Phenylcarbonylamino)-4-(1-Hydroxymethylphenyl)-1,2,3,6-Tetrahydropyridines, Med.Chem. Res. 1997, 7(1), 1-15.

4.Y.M. Hiiji, P.F. Hudrlik, C.O. Okoro, and A.M. Hudrlik. “Preparation of O-(Silyl)Benzyl Alcohols” Synth. Commun. 1997, 27, 4297-4308

5.                    Cosmas O.Okoro, Kyoung Jin P.Yoon, Tiffany L. Wilson, Udobi C. Onubogu, Tanya S. Eckford and Kinfe K. Redda. “Synthesis and Biological Evaluation of N-(Substituted Benzoylamino)-5-carbethoxymethyl -1,2,3,6-Tetrahydropyridines as Potential Anti-inflammatory and Hyperglycemic Agents.” Med. Chem. Res. 1999, 9(2) 133-148.

6.                    P.F. Hudrlik, J.O. Arango, Y.M. Hijji, C.O. Okoro and A.M. Hudrlik.  “Alkoxides of O-Silyl Benzyl Alcohols in Cleavage Reactions: Approaches to Benzyl and Silyl Anion Equivalents.” Can. J. Chem. 2000, 78, 1421-1427

7.                    P.F. Hudrlik, C.O. Okoro, and A.M. Hudrlik. “Generations of a Silyl Anion Equivalent by Intramolecular Alkoxide Attack at Silicon.” NIGMS Symposium 1991, 483, 130.

8.                    P.F. Hudrlik, Y.M. Abdallah, C.O. Okoro and A.M. Hudrlik.” Rearrangemnet of Organosilicon Compounds.” ACS Symposium Series 1992, 242.

9.                    P.F. Hudrlik, Y.M. Abdallah, C.O. Okoro and A.M. Hudrlik. “ Benzyloxysilanes Cleavage and Rearrangement Reactions.” XXVII Organosilicon Symposium 1993, G10.

10.                 C. A. Pelle, C.O. Okoro, T.L. Wilson, U.C. Onubogu, K.J. Yoon, and K.K. Redda. “ Synthesis and Characterization of Several N-(Substituted Phenylcarbonylamino)-4-Cyclohexenyl-1,2,3,6-Tetrahydropyridines.” NIGMS Symposium 1995, A-11, 5.

11.                 C.O.Okoro, U.C. Onubogu, T.S. Eckford, C.A. Pelle, T.L. Wilson and K.K. Redda.  “The Synthesis and Biological Evaluation of N-(Substituted-Phenylcarbonylamino)-3-Carboethoxymethyl-1,2,3,6-Tetrahydropyridine as Potential Anti-inflammatory and Hyperglycemic Agents.” 210th ACS National Meeting, Chicago, Aug.20-24, 1995, MEDI 90.

12.                 C.O. Okoro, T.L. Wilson, J. Choi and K.K. Redda. “ Synthesis of N-(Substituted –Phenylcarbonylamino)-4-(1-Hydroxymethylphenyl)-1,2,3,6-Ttrahydropyridines as Potential Hyperglycemic and Anti-inflammatory Agents. NIGMS Symposium 1995, A-12, 5.

13.               C.O.Okoro. “The Role of Chemistry and Chemicals in Health and Medicine.” University of Arkansas Pine Bluff-National Center for Toxicological Research Biomedical Seminar Series, April 13, 1998.

14.               C.O.Okoro and G.L. Grunewald. “Synthesis of 7-N-ethylsulfonyl-1,2,3,4-tetrahydroisoquinoline as Selective Inhibitor of Phenylethanolamin-N-Methyltransferase (PNMT) versus a2 –Adrenoceptor Affinity.” 23rd Annual Research Symposium, Tennessee State University, March 20-21, 2001.

15.              Patrice Jackson and C. O. Okoro. “ Fluorinated Enaminones as reactive intermediates in Organic Synthesis.” 24th Annual Research Symposium, Tennessee State University, March 19-20, 2002.

16.               Cosmas O. Okoro, Tifanny L. Wilson, and Kinfe K. Redda. “Conformational    Analysis and Molecular Properties of N-(Substituted Phenylcarbonylamino)-4-(1-hydroxymethylphenyl)-1,2,3,6-tetrahydropyridines, Current Medicinal Chemistry, 2003, 10. 313-320.

17.              Cosmas O.Okoro and Patrice L. Jackson, “Synthesis, Conformational Analysis and Molecular Properties of New Trifluoromethyl Enaminone”, Abstracts, 55th Southeast Regional Meeting of the American Chemical Society, Atlanta, GA, United States, November 16-19, 2003 (2003), 565. Publisher, American Chemical Society, Washington, D.C. CODEN: 69EUCH Conference; Meeting Abstract written in English. AN2004: 129444. CAPLUS (Copyright 2004 ACS on SciFinder(R)).

18.                 Jessica Gadsden, Elaine Sanders-Bush, and Cosmas Okoro, “Acute Clozapine exposure does not desensitize 5-HT2C Receptors in vitro”, Abstracts, 55th Southeast Regional Meeting of the American Chemical Society, Atlanta, GA, United States, November 16-19, 2003 (2003), 167. Publisher, American Chemical Society, Washington, D.C. CODEN: 69EUCH Conference; Meeting Abstract written in English. AN2004: 132310. CAPLUS (Copyright 2004 ACS on SciFinder(R)).

19.                 Farmer, Takeisha L.; Okoro, Cosmos O. “Synthesis, Comformational Analysis, and Molecular properties of Methyl 4-[(Substituted phenyl)amino]-2-oxo-6-trifluoromethyl)cyclohex-3-ene-1-oates” Abstracts, 57th Southeast/61st Southwest joint Regional Meeting of the American Chemical Society, Memphis, TN, United States, November 1-4 (2005), NOV04-415: Publisher: American Chemical Society, Washington, D. C. CODEN: 69 HOKM Conference; Meeting Abstract written in English.  AN 2005:1225106 CAPLUS (Copyright(C)2005 ACS on ScFinder (R))

20.               Brown, Patrick; Okoro, Cosmos O. “Pharmacophore Analysis of hSert and hNet inhibitors” Abstracts, 57th Southeast/61st Southwest joint Regional Meeting of the American Chemical Society, Memphis, TN, United States, November 1-4 (2005), NOV04-402: Publisher: American Chemical Society, Washington, D. C. CODEN: 69HOKM Conference; Meeting Abstract written in English.  AN 2005:1225093 CAPLUS (Copyright(C)2005 ACS on ScFinder (R))

21.             Gary L. Grunewald, Jian Lu, Kevin R. Criscione and Cosmas O. Okoro, Inhibitors of phenylethanolamine N-methyltransferase devoid of α2 –adrenoceptor affinity. Bioorganic & Medicinal Chemistry Letters 15 (2005) 5319-5323.

22.              Cosmas O. Okoro, Olugbeminiyi O. Fadeyi, Patrice L. Jackson, Rhonda L. Richmond, and Takeisha Farmer, Synthesis of fluorinated cyclic s-trans vinylogous acid and amide ester derivatives. Tetrahedron Letters 47 (2006) 7451-7454.

23.              Olugbeminiyi O. Fadeyi, and Cosmas O. Okoro, “Synthesis and reactions of Fluorinated Cyclic s-Trans Vinylogous acids and Amides: Palladium-catalyzed coupling of fluorinated cyclic s-trans enaminone with aryl and heteroaromatic halides”. Journal of the Tennessee Academy of Science, Vol 81, No. 3-4, page 88 (2006).

24.               Saudat T. Adamson, Olugbeminiyi O. Fadeyi, Elber L. Myles and Cosmas O.  Okoro, “The anticancer effects of some West African medicinal plants”. Journal of the Tennessee Academy of Science, Vol 81, No. 3-4, page 89 (2006).

25.              Olugbeminiyi O. Fadeyi, Carolyn Cummings,  Saudat T. Adamson, Cosmas O. Okoro, and E. Lewis Myles, “Isolation and characterization of the active components of Setaria Megaphylla”. Journal of the Tennessee Academy of Science, Vol 81, No. 3-4, page 89 (2006).

26.             Fadeyi, Olugbeminiyi O.; Wash, Kendra; Okoro, Cosmas O.. Synthesis of fluorinated dihydropyrazolo-pyrimidine derivatives as potential biologically active compounds. Abstracts of Papers, 233rd ACS National Meeting, Chicago, IL, United States, March 25-29, 2007  (2007), MEDI-408.  CODEN: 69JAUY  AN 2007:295837 CAPLUS

27.             Olugbeminiyi O. Fadeyi, Cosmas O. Okoro. Synthesis of 5-(trifluoromethyl)cyclohexane-1,3-dione and 3-amino-5-(trifluoromethyl)cyclohex-2-en-1-one: new trifluoromethylbuilding block. Tetrahedron Lett. 49 (2008) 4725-4727.

28.             Olugbeminiyi O. Fadeyi, Saudat T. Adamson, E. Lewis Myles, Cosmas O. Okoro. Novel fluorinated acridone derivatives. Part 1: Synthesis and evaluation as potential anticancer agents. Bioorganic & Medicinal Chemistry Letters 18 (2008) 4172-4176.